Ibuprofen Side Effects Long-term – Ibuprofen was first introduced to the general public in 1969 and until now has become a popular drug for relieving pain or fever in both older persons and children. This type of ibuprofen drug is a drug that is quite safe for consumption as long as the dosage is appropriate.
The workings of ibuprofen can be explained as follows, in general, the body secretes the cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2) enzymes. Both of these enzymes will trigger the prostagaldin hormone.
This hormone that appears will then send information to the brain about the existence of stimuli that can trigger inflammation about pain that appears in the area that sends the signal. The ibuprofen that we drink functions to block the cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2) enzymes, so signals are sent to the brain.
In general, drugs with this type of ibuprofen can be found easily in pharmacies throughout Indonesia and this drug is categorized as an over-the-counter drug.
However, in its use, you must still follow the recommendations because if used excessively and in the long term it can harm the health of the body.
Ibuprofen Side Effects Long-term
The following are side effects if you consume ibuprofen too often.
1. Stomachache
One of the side effects of consuming too much ibuprofen is stomach pain and also problems with the intestines when taken too often and too much. Ibuprofen can also cause peptic ulcer develops The duodenum is the part of the intestine that lies behind the stomach. Ibuprofen will reduce the production of prostaglandin hormones.
This prostaglandin hormone is responsible for increasing the production of gastric mucus and substances that make stomach acid neutral. Taking ibuprofen too often can cause the production of prostalgadin to decrease so that the stomach is vulnerable to damage caused by stomach acid.
2. Vomiting
Vomiting is one of the Ibuprofen Side Effects Long-term. Ibuprofen may increase the risk of indigestion due to reduced prostaglandin hormone production as described above. Besides being able to cause stomach pain, other effects are nausea and even vomiting due to rising stomach acid.
For this reason, even though this drug is sold freely, we still have to consume it in the recommended dosage so as not to bring bad side effects.
3. Heart Attack
Although this side effect is very rare, if ibuprofen is consumed in large doses and continuously it can pose a risk of heart attack getting higher.
Even if people who often take ibuprofen have congenital heart risk factors, the risk level will be even higher. For this reason, to be safe, for those of you who have these risk factors, you should consult with your doctor about your condition as clearly as possible so that you can avoid conditions that are harmful to your health.
4. Strokes
Strokes is one of the Ibuprofen Side Effects Long-term. Too often consuming high doses of ibuprofen can also cause strokes. This is because ibuprofen consumed in excessive doses can cause hypertension to become more severe.
This high blood pressure can increase the risk of stroke, therefore if you often feel dizzy and uncomfortable, before taking medication, you should first consult with your doctor so that the drug can help relieve pain, not make it worse.
5. High Blood Pressure
High blood pressure is one of the Ibuprofen Side Effects Long-term. Ibuprofen has been known to cause high blood pressure, when consumed in high doses and continuously. This is due to changes in prostaglandin levels in the body due to ibuprofen.
This can make the fluids in the body unstable, which in turn makes the risk of high blood pressure appear. This will be exacerbated if our lifestyle is unhealthy, such as smoking, rarely exercising and experiencing excess weight.
6. Stomach Wounds
Stomach wounds is one of the Ibuprofen Side Effects Long-term. Too often consuming high doses of ibuprofen can affect the level of prostaglandin hormones in the body to decrease. This condition makes the mucus in the stomach decrease and in the end the fluid in the stomach decreases and this risk can cause injury to the stomach.
7. Liver failure
Liver Failuer is one of the Ibuprofen Side Effects Long-term. Excessive use of ibuprofen can also lead to liver failure. Ibuprofen has been reported to cause liver failure, even if severe enough to result in need liver transplant must be done to save the patient’s life.
Even if this condition is not handled properly and quickly it can cause the risk of death for these patients. However, if ibuprofen is taken in the proper dosage, this drug is classified as a safe drug for consumption.
8. Exacerbates Asthma
Exacerbates asthma is one of the Ibuprofen Side Effects Long-term. People who suffer from asthma should be careful when consuming ibuprofen, especially in frequent amounts. Ibuprofen can cause breathing sounds or even shortness of breath and can worsen the condition of someone who already has asthma.
This condition is caused because ibuprofen can cause the airways to become narrow. This condition is also known as bronchospasm.
Normal Dosage of Ibuprofen Consumption
If you are taking ibuprofen or any medicine, we should follow the recommendations. If it is an over-the-counter drug, the instructions for use will be written on the package, which we must follow and understand.
And if the pain or ache doesn’t get better, it’s better for us to consult a doctor to be able to get the best treatment. The following are the normal recommended doses when taking Ibuprofen in older persons and children.
| Patients | Ibuprofen | Dosage |
|---|---|---|
| Older persons | Pain Reliever | 200-400 mg, every 4-6 hours |
| Anti-inflammatory | 300 mg, every 6-8 hours or 400-800 mg 3-4 times a day | |
| Children | Pain Reliever | 5-10 mg/kg. Every 6 hours (max. 40 mg/kg per day) |
| Anti-inflammatory | 20-40 mg/kg/day, 3-4 times daily. |
